Piperidine → HCID 9907843, 화합물

HRID 48394노트

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HRID 48394 반응식
[CH3:1][C:2]1[C:7](=[O:8])[C:6]([CH3:9])=[C:5]([CH3:10])[C:4](=[O:11])[C:3]=1[CH2:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][C:21](O)=[O:22])=[CH:15][CH:14]=1.[NH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH3:1][C:2]1[C:7](=[O:8])[C:6]([CH3:9])=[C:5]([CH3:10])[C:4](=[O:11])[C:3]=1[CH2:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][C:21]([N:24]2[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]2)=[O:22])=[CH:15][CH:14]=1

참가 물질

3

반응물 2

HCID 8082PiperidineHCID 106150173-[4-(3,5,6-Trimethyl-1,4-benzoquinon-2-ylmethyl)phenyl]propionic acid

생성물 1

HCID 9907843HCID 9907843, 화합물수율 175%

실험 절차

3-[4-(3,5,6-trimethyl-1,4-benzoquinon-2-ylmethyl)phenyl]propionic acid (25 mg, 0.08 mmol) and piperidine (0.012 ml, 0.12 mmol) were used, and a method similar to that described in Production Example 46 was employed to obtain the title compound (53 mg, 0.14 mmol, yield 59%).

출처 및 근거

ORD 기록
ord-043a223244ba48daa178ef2cde9e20a9
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06703421B1

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