Sodium Iodide → HCID 14856141, 화합물

HRID 484133

반응식

HRID 484133 반응식
[CH3:1][CH:2]1[N:6]([CH2:7][CH2:8][CH2:9][CH2:10]Br)[C:5](=[O:12])[CH2:4][S:3]1.Cl.[Cl:14][C:15]1[CH:16]=[C:17]([N:21]2[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]2)[CH:18]=[CH:19][CH:20]=1.C([O-])([O-])=O.[K+].[K+].[Na+].[I-]>CC#N>[ClH:14].[Cl:14][C:15]1[CH:16]=[C:17]([N:21]2[CH2:26][CH2:25][N:24]([CH2:10][CH2:9][CH2:8][CH2:7][N:6]3[C:5](=[O:12])[CH2:4][S:3][CH:2]3[CH3:1])[CH2:23][CH2:22]2)[CH:18]=[CH:19][CH:20]=1

참가 물질

6

반응물 4

HCID 5238Sodium IodideHCID 11430Potassium CarbonateHCID 256811-(3-Chlorophenyl)piperazine monohydrochlorideHCID 10490993HCID 10490993, 화합물

생성물 1

HCID 14856141HCID 14856141, 화합물

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

To a solution of 2-methyl-3-(4-bromobutyl)-4-thiazolidinone (4.0 g) and 1-(3-chlorophenyl)piperazine hydrochloride (3.69 g) in 100 ml of dry CH3CN were added K2CO3 (8.8 g) and NaI (200 mg). The mixture was heated to reflux with stirring under N2.

후처리

  1. temperatureThe mixture was heated
  2. temperatureto reflux

출처 및 근거

ORD 기록
ord-cdb7f52b6fce491cb6a68b9af66b91eb
출처 데이터셋
uspto-grants-1993_07
특허 번호
US05229388

연결된 노트

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