Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Myristyl bromide → 3-(Tetradecyloxy)benzenemethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Myristyl bromide | HCID 8208 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 3-Hydroxyphenethyl alcohol | HCID 83404 | — |
| 촉매 | Trioctylmethylammonium chloride | HCID 21218 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 3-(Tetradecyloxy)benzenemethanol | HCID 10041710 | 652.2% |
반응 단계
A mixture of 66 g of 3-hydroxyphenethyl alcohol, 147.43 g of 1-bromotetradecane, 27.65 g of sodium hydroxide and 2.15 g of trioctylmethyl ammonium chloride in 400 ml of toluene was refluxed for 42 hours. The mixture was washed with water and the organic layer dried with magnesium sulfate. The solvent was removed in vacuo and the warm concentrate poured into 1 liter of hexanes. The resulting solid was washed with cold hexanes then dried giving 998.6 g of the desired compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05231091 |
| 출처 데이터셋 | uspto-grants-1993_07 |
| ORD ID | ord-1161c2df0c8046888a26a9778defb941 |
| 출처 메모 | uspto-grants-1993_07 |