Alanine-methacrylamide → HCID 178449942, 화합물

HRID 48454노트

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HRID 48454 반응식
[C:1]([NH2:6])(=[O:5])[C:2]([CH3:4])=[CH2:3].[NH2:7][C@H:8]([C:10]([OH:12])=[O:11])[CH3:9].Cl.[C:14]([NH2:19])(=[O:18])[C:15]([CH3:17])=[CH2:16].[NH2:20][C@H:21]([C:29]([OH:31])=[O:30])[CH2:22][CH2:23][CH2:24][NH:25][C:26](=[NH:28])[NH2:27]>O.CO>[C:1]([NH2:6])(=[O:5])[C:2]([CH3:4])=[CH2:3].[NH2:7][C@H:8]([C:10]([OH:12])=[O:11])[CH3:9].[C:14]([NH2:19])(=[O:18])[C:15]([CH3:17])=[CH2:16].[NH2:20][C@H:21]([C:29]([OH:31])=[O:30])[CH2:22][CH2:23][CH2:24][NH:25][C:26](=[NH:27])[NH2:28]

참가 물질

5

반응물 2

HCID 86759378Alanine-methacrylamideHCID 178449946HCID 178449946, 화합물

생성물 1

HCID 178449942HCID 178449942, 화합물

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

실험 절차

Alanine-methacrylamide(2.20 g) and 1.67 g of arginine-methacrylamide hydrochloride were dissolved in 15 ml of water, added 0.167 g of the fluorescence-labeled monomer dissolved in 15 ml of methanol, and bubbled with nitrogen gas for 1 hour. Potassium persulfate(0.060 g) was added to and dissolved in this solution, and the solution was refluxed by heating for 3 hours while maintaining nitrogen gas bubbling. The reaction mixture was poured into isopropanol to form precipitates. The supernatant was removed by decantation, and acetone was added again to the precipitates, and obtained mixture was stirred vigorously. The produced precipitates (powdered form) were collected by filtration, washed with acetone, and dried to obtain the target polymer.

후처리

  1. custombubbled with nitrogen gas for 1 hour
  2. additionPotassium persulfate(0.060 g) was added to and
  3. dissolutiondissolved in this solution
  4. temperaturethe solution was refluxed
  5. temperatureby heating for 3 hours
  6. temperaturewhile maintaining nitrogen gas
  7. custombubbling
  8. additionThe reaction mixture was poured into isopropanol
  9. customto form
  10. customprecipitates
  11. customThe supernatant was removed by decantation, and acetone
  12. additionwas added again to the precipitates
  13. customobtained mixture
  14. customThe produced precipitates (powdered form)
  15. filtrationwere collected by filtration
  16. washwashed with acetone
  17. customdried
  18. customto obtain the target polymer

출처 및 근거

ORD 기록
ord-4fe74769f9ed4d4ca60585b4d08e08ae
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06703468B1

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