Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-[Bis(4-fluorophenyl)methylene]-1-(phenylmethyl)piperidine → 4-(Bis(4-fluorophenyl)methylene)piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-[Bis(4-fluorophenyl)methylene]-1-(phenylmethyl)piperidine | HCID 13519965 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-(Bis(4-fluorophenyl)methylene)piperidine | HCID 2724436 | — |
반응 단계
A mixture of 1.6 parts of 4-[bis(4-fluorophenyl)methylene]-1-(phenylmethyl)piperidine and 80 parts of methanol was hydrogenated at normal pressure and at room temperature with 1 part of rhodium-on-charcoal catalyst 5%. After the calculated amount of hydrogen was taken up, the catalyst was filtered off and the filtrate was evaporated, yielding 1.2 parts of 4-[bis(4-fluorophenyl)methylene]piperidine as a residue (intermediate 14).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04533665 |
| 출처 데이터셋 | uspto-grants-1985_08 |
| ORD ID | ord-f88207d3b9354acea8607188c4eb2351 |
| 출처 메모 | uspto-grants-1985_08 |