Methanol → Methyl 2-bromo-4-methylpentanoate

반응식

[Br:1][CH:2]([CH2:6][CH:7]([CH3:9])[CH3:8])[C:3](Cl)=[O:4].[CH3:10][OH:11]>>[CH3:10][O:11][C:3](=[O:4])[CH:2]([Br:1])[CH2:6][CH:7]([CH3:9])[CH3:8]

참가 물질

반응물 2

HCID 887Methanol

HCID 135203652-Bromo-4-methylpentanoyl chloride

생성물 1

HCID 12957039Methyl 2-bromo-4-methylpentanoate

실험 절차

2-Bromo-4-methylpentanoyl chloride (IV, Example 2) is added dropwise to methyl alcohol (200 ml.) at 0°. After two hours the methanol is removed under reduce pressure and the residual oil is partitioned between chloroform and water. The chloroform is separated from the water and removed under reduced pressure to give a residual oil which is distilled under reduced pressure to give the title compound, b.p. 78°-90°/30 mm.

후처리

customAfter two hours the methanol is removed
customthe residual oil is partitioned between chloroform and water
customThe chloroform is separated from the water
customremoved under reduced pressure
customto give a residual oil which
distillationis distilled under reduced pressure

출처 및 근거

ORD 기록: ord-ef708403d1f1434c8a3eed888161b871
출처 데이터셋: uspto-grants-1985_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04534897

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