Sodium Acetate → 2-Methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl acetate

HRID 485120노트

반응식

HRID 485120 반응식
C(O[C:5]1([CH3:14])[CH:9]=[CH:8][C:7](=[O:10])[CH:6]1[CH2:11][CH:12]=[CH2:13])(=O)C.[C:15]([O-:18])(=[O:17])[CH3:16].[Na+]>C(O)(=O)C>[C:15]([O:18][CH:9]1[CH2:8][C:7](=[O:10])[C:6]([CH2:11][CH:12]=[CH2:13])=[C:5]1[CH3:14])(=[O:17])[CH3:16]

참가 물질

4

반응물 2

HCID 517045Sodium AcetateHCID 13335393HCID 13335393, 화합물

생성물 1

HCID 131027602-Methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl acetate수율 176.3%

시약·촉매·용매 1

HCID 176Acetic Acid용매2회

실험 절차

Into a four necked flask equipped with an agitator and a thermometer, 3-acetoxy-2-allyl-3-methyl-4-cyclopentenone (19.4 g), acetic acid (80 ml) and sodium acetate (4 g) were charged and refluxed for 5 hours with agitation. After the completion of the reaction, acetic acid was evaporated off under reduced pressure. The residue was shaken with toluene (70 ml) and water (40 ml). The organic layer was separated, washed with an aqueous solution of sodium bicarbonate and then water and concentrated. The residue was distilled to obtain 4-acetoxy-2-allyl-3-methyl-2-cyclopentenone (16.7 g). Yield, 86%. B.P., 100°-110° C./0.1-0.3 mmHg.

후처리

  1. customInto a four necked flask equipped with an agitator
  2. temperaturerefluxed for 5 hours with agitation
  3. customwas evaporated off under reduced pressure
  4. customThe organic layer was separated
  5. washwashed with an aqueous solution of sodium bicarbonate
  6. concentrationwater and concentrated
  7. distillationThe residue was distilled

출처 및 근거

ORD 기록
ord-83a2d24f388e4c3ea1585f823b98d8f1
출처 데이터셋
uspto-grants-1985_08
특허 번호
US04535182

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