Sodium Acetate → 2-Methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl acetate

HRID 485123노트

반응식

HRID 485123 반응식
[CH2:1]([CH:4]1[C:8](O)([CH3:9])[CH:7]=[CH:6][C:5]1=[O:11])[CH:2]=[CH2:3].[C:12]([O-:15])(=[O:14])[CH3:13].[Na+]>C(O)(=O)C>[C:12]([O:15][CH:7]1[CH2:6][C:5](=[O:11])[C:4]([CH2:1][CH:2]=[CH2:3])=[C:8]1[CH3:9])(=[O:14])[CH3:13]

참가 물질

4

반응물 2

HCID 517045Sodium AcetateHCID 128798724-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one

생성물 1

HCID 131027602-Methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl acetate수율 390.7%

시약·촉매·용매 1

HCID 176Acetic Acid용매2회

실험 절차

In the same apparatus as in Example 1, 2-allyl-3-hydroxy-3-methyl-4-cyclopentenone (15.2 g), acetic acid (45 ml) and sodium acetate (2 g) were charged and heated to reflux for 7 hours. After the completion of the reaction, acetic acid was evaporated off under reduced pressure. The residue was extracted with toluene (60 ml) and water (40 ml) and treated as in Example 1 to obtain 4-acetoxy-2-allyl-3-methyl-2-cyclopentenone (18.5 g). Yield, 95.3%. B.P., 100°-110° C./0.1-0.3 mmHg.

후처리

  1. temperatureheated
  2. temperatureto reflux for 7 hours
  3. customwas evaporated off under reduced pressure
  4. extractionThe residue was extracted with toluene (60 ml) and water (40 ml)
  5. additiontreated as in Example 1

출처 및 근거

ORD 기록
ord-b15c076b8b4a46448ada65822b435708
출처 데이터셋
uspto-grants-1985_08
특허 번호
US04535182

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