Acetic Acid → HCID 13335396, 화합물

반응식

O[C:2]1([CH3:13])[CH:6]=[CH:5][C:4](=[O:7])[CH:3]1[CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[C:14]([OH:17])(=[O:16])[CH3:15]>>[CH2:8]([C:3]1[C:4](=[O:7])[CH2:5][CH:6]([O:17][C:14](=[O:16])[CH3:15])[C:2]=1[CH3:13])[CH2:9][CH2:10][CH2:11][CH3:12]

참가 물질

반응물 2

HCID 176Acetic Acid2회

HCID 13137234HCID 13137234, 화합물

생성물 1

HCID 13335396HCID 13335396, 화합물

실험 절차

In the same apparatus as in Example 1, 3-hydroxy-2-n-pentyl-3-methyl-4-cyclopentenone (18.2 g) and acetic acid (55 ml) were charged and heated under reflux for 15 hours with agitation. After the completion of the reaction, acetic acid was evaporated off under reduced pressure. The residue was extracted with toluene (80 ml) and water (50 ml) and treated as in Example 1 to obtain 2-n-pentyl-3-methyl-4-acetoxy-2-cyclopentenone (20.6 g). Yield, 92%. B.P., 125°-135° C./0.2-0.5 mmHg.

후처리

temperatureheated
temperatureunder reflux for 15 hours with agitation
customwas evaporated off under reduced pressure
extractionThe residue was extracted with toluene (80 ml) and water (50 ml)
additiontreated as in Example 1

출처 및 근거

ORD 기록: ord-b325d5c9d338437b99c94e3fe3a683b5
출처 데이터셋: uspto-grants-1985_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04535182

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