[CH3:1][NH:2]/[C:3](/[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[C:4]1\[C:5](=[O:13])[C:6]2[CH:12]=[CH:11][CH:10]=[CH:9][C:7]=2S\1.OO.[S:22]([O-:25])([O-])=[O:23].[Na+].[Na+]>C(O)(=O)C>[CH3:1][NH:2]/[C:3](/[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[C:4]1\[C:5](=[O:13])[C:6]2[CH:12]=[CH:11][CH:10]=[CH:9][C:7]=2[S:22]\1(=[O:25])=[O:23]A mixture of 6.0 gm (0.0224 mol) of (E)-2-[(methylamino)phenylmethylene]-benzo[b]thiophen-3(2H)-one, 100 ml of glacial acetic acid and 3.5 ml (0.034 mol) of an aqueous 30% hydrogen peroxide solution was heated at 50° C. for four hours while stirring and then allowed to stand overnight at room temperature. After the addition of 40 ml of a 10% sodium sulfite solution, the mixture was concentrated by evaporation in vacuo, and the residue was suspended in 200 ml of water. The solid material precipitated thereby was suction-filtered off and then broken down into its constituents by column chromatography on 300 gm of silica gel, using 1,2-dichloroethane/ethyl acetate (97:3 v/v) as the eluant. By evaporating the appropriate fractions, 2.0 gm (33% of theory) of pale yellow (E)-2-[(methylamino)phenylmethylene]-benzo[b]thiophen-3(2H)-one-1-oxide, m.p. 205-206° C (decomposition) from ethanol), and 0.10 gm (1.5% of theory) of light yellow (E)- 2-[(methylamino)phenylmethylene]-benzo[b]-thiophen-3(2H)-one-1,1-dioxide, m.p. 302°-303° C., were obtained.
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