4-Amino-2-methylpyrimidine-5-carbaldehyde → 4-Amino-2-methyl-5-pyrimidinemethanamine
반응식
[CH3:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([CH:9]=O)=[CH:4][N:3]=1.[NH3:11].CO>O[Mo](O)(=O)=O>[CH3:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([CH2:9][NH2:11])=[CH:4][N:3]=1참가 물질
4
실험 절차
Into an Erlenmeyer's flask of 100 ml, 2.00 g (14.6 millimole) of 2-methyl-4-amino-5-formylpyrimidine, 40 g of 20 wt. % ammonia-methanol solution and 2.0 mg of molybdic acid (H2MoO4.H2O) were added, and the mixture was stirred for 2 hours under room temperature, with the flask being closely stoppered. Following subsequently the same procedure as in Example 1, 2-methyl-4-amino-5-aminomethylpyrimidine was obtained at a yield of 93.5%.
출처 및 근거
- ORD 기록
- ord-c829ba66a22041189243bf237dd00d53
- 출처 데이터셋
- uspto-grants-1985_08
- 특허 번호
- US04536577
반응 노트
불러오는 중…