Methan(2H)ol → 1-(4-Methoxyphenyl)-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid
반응식
C([O:3][C:4]([C:6]1[C:10](=[O:11])[NH:9][N:8]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH:7]=1)=[O:5])C.CO[2H]>>[CH3:19][O:18][C:15]1[CH:14]=[CH:13][C:12]([N:8]2[CH:7]=[C:6]([C:4]([OH:5])=[O:3])[C:10](=[O:11])[NH:9]2)=[CH:17][CH:16]=1참가 물질
3
실험 절차
The ester prepared as described above in (a) was converted to the title acid in a manner analogous to example 11(b). The acid possessed νmax (nujol) 1690, 1670, 1599, 1580, 1575,cm-1, δ(CH3OD|D6DMSO) 3.78 (3H,s,--OMe), 7.00 (2H,d,J9 Hz, protons o to --OMe), 7.66 (2H,d,J9 Hz, protons m to --OMe), 8.45(1H,s, C3 -pyrazole proton). Found: M30, 234.0639; C11H10N2O4 requires M,234.0641.
출처 및 근거
- ORD 기록
- ord-3397bc01df18497792a0ad9bbb5eb50d
- 출처 데이터셋
- uspto-grants-1985_08
- 특허 번호
- US04537886
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