Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Barium → 4-(1H-Imidazol-2-yl)-pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Barium | HCID 5355457 | — |
| 반응물 | 4-(4,5-dihydro-1H-imidazol-2-yl)pyridine | HCID 11159387 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-(1H-Imidazol-2-yl)-pyridine | HCID 316817 | 68.1% |
반응 단계
2-(4-pyridyl)-imidazoline (7.0 g, 0.047M) and barium mangnate (52.5 g) in CH2Cl2 (500 ml) were refluxed with stirring for 24 hrs. The reaction mixture was then filtered through diatomaceous earth, washed with methylene chloride and then ethylacetate. The combined filtrates were concentrated and crystallized from ethylacetate-petroleum ether to give 4-(1H-imidazol-2-yl)pyridine (4.7 g, 67% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04537969 |
| 출처 데이터셋 | uspto-grants-1985_08 |
| ORD ID | ord-0bfd84af59824f4c899639b3004aa7ad |
| 출처 메모 | uspto-grants-1985_08 |