Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methylthiomethyl-3,4,6-trifluoroaniline → 3,4,6-Trifluoro-2-methylaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methylthiomethyl-3,4,6-trifluoroaniline | HCID 18974461 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3,4,6-Trifluoro-2-methylaniline | HCID 22625178 | 71.3% |
반응 단계
To 2-methylthiomethyl-3,4,6-trifluoroaniline (22.2 g) are added ethanol (400 ml) and Raney nickel (200 g) and the mixture is stirred at room temperature for 30 minutes. After the catalyst is filtered off, the filtrate is added with water and extracted with dichloromethane. The is dried over magnesium sulfate and concentrated to give 2-methyl-3,4,6-trifluoroaniline (12.3 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05290934 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-65a42f8c16c84334b479a3ff0c9274d7 |
| 출처 메모 | uspto-grants-1994_03 |