Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopropylamine → HCID 178418304, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopropylamine | HCID 69828 | — |
| 반응물 | Ethyl 2-(2,4,5-trifluoro-6-methylbenzoyl)-3-ethoxyacrylate | HCID 54242925 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | HCID 178418304 | HCID 178418304 | — |
반응 단계
Ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate (3.5 g) is dissolved in ethanol (25 ml) and thereto cyclopropylamine (0.84 ml) is added dropwise under ice-cooling. After stirring at room temperature for 30 minutes, the mixture is concentrated and the residue is purified with column chromatography (silica-gel, dichloromethane: n-hexane =1 : 1) to give ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-cyclopropylaminoacrylate (2.7 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05290934 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-0ba2144ac4a2481783da45fbc16a8c82 |
| 출처 메모 | uspto-grants-1994_03 |