Imidazole → Silane, [(8-bromooctyl)oxy](1,1-dimethylethyl)dimethyl-

HRID 486318노트

반응식

HRID 486318 반응식
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][OH:10].N1C=CN=C1.[CH3:16][Si:17]([CH3:23])([C:19]([CH3:22])([CH3:21])[CH3:20])Cl>CN(C)C=O>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][O:10][Si:17]([CH3:23])([CH3:16])[C:19]([CH3:22])([CH3:21])[CH3:20]

참가 물질

5

반응물 3

HCID 795ImidazoleHCID 28928tert-Butyldimethylsilyl chlorideHCID 1626071-Octanol, 8-bromo-

생성물 1

HCID 10969362Silane, [(8-bromooctyl)oxy](1,1-dimethylethyl)dimethyl-수율 88%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

One operates as in preparation 13 starting with 3.97 g of 8-bromooctanol, 19 cm3 of dimethylformamide, 1.55 g of imidazole and 3.32 g of dimethyl tertbutyl chlorosilane. After chromatography on silica (eluant: cyclohexane--toluene 8-2), one obtains 5.4 g of the expected product.

출처 및 근거

ORD 기록
ord-0f0d8e0e2e0447f9bd5e1362dd53fad7
출처 데이터셋
uspto-grants-1994_03
특허 번호
US05290771

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