Pyridine → 3-Amino-5-[3-(pentylthio)propylthio]-1,2,4-triazole
반응식
[CH2:1]([S:6][CH2:7][CH2:8][CH2:9]Cl)[CH2:2][CH2:3][CH2:4][CH3:5].[NH2:11][C:12]1[N:16]=[C:15]([SH:17])[NH:14][N:13]=1.N1C=CC=CC=1.NC1N=C(SCCSCCSCCCCCC)NN=1>C(#N)C.O>[NH2:11][C:12]1[N:16]=[C:15]([S:17][CH2:9][CH2:8][CH2:7][S:6][CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])[NH:14][N:13]=1참가 물질
7
실험 절차
Compound 9 was prepared from a mixture of 3-chloropropyl pentyl sulfide, 3-amino-5-mercapto-1,2,4-triazole and pyridine in acetonitrile, as described previously for Compound 12. The reaction mixture was poured into water and extracted with CH2Cl2. The extracts were washed with water and brine, dried over MgSO4, and concentrated under vacuum to provide Compound 9 in 71% yield.
후처리
- extractionextracted with CH2Cl2
- washThe extracts were washed with water and brine
- dry with materialdried over MgSO4
- concentrationconcentrated under vacuum
출처 및 근거
- ORD 기록
- ord-e6c26a24494a483faac30057276f6133
- 출처 데이터셋
- uspto-grants-1994_03
- 특허 번호
- US05292627
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