Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-tert-Butylbenzenesulfonamide → p-tert-butyl-N-[6-(2-hydroxyethoxy)-5(o-methoxyphenoxy)-2-(trifluoromethyl)-4-pyrimidinyl]benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-tert-Butylbenzenesulfonamide | HCID 222872 | — |
| 반응물 | 4,6-Dichloro-5-(2-methoxyphenoxy)-2-trifluoromethylpyrimidine | HCID 18184264 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | p-tert-butyl-N-[6-(2-hydroxyethoxy)-5(o-methoxyphenoxy)-2-(trifluoromethyl)-4-pyrimidinyl]benzenesulfonamide | HCID 19095722 | — |
반응 단계
By reacting 4,6-dichloro-5-(2-methoxyphenoxy)-2-trifluoromethylpyrimidine with p-tert-butylbenzenesulfonamide and with ethylene glycol Na there was obtained p-tert-butyl-N-[6-(2-hydroxyethoxy)-5(o-methoxyphenoxy)-2-(trifluoromethyl)-4-pyrimidinyl]benzenesulfonamide, m.p. 190°-192° C. (from toluene). Sodium salt: M.p. 288°-289° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05292740 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-fdd360d13d074b359c24049046676f2f |
| 출처 메모 | uspto-grants-1994_03 |