4-Chlorobenzenesulfonamide → 4-chloro-N-[6-chloro-5-(5-fluoro-2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide
반응식
Cl[C:2]1[C:7]([O:8][C:9]2[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=2[O:16][CH3:17])=[C:6]([Cl:18])[N:5]=[CH:4][N:3]=1.[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([S:26]([NH2:29])(=[O:28])=[O:27])=[CH:22][CH:21]=1>>[Cl:19][C:20]1[CH:21]=[CH:22][C:23]([S:26]([NH:29][C:2]2[C:7]([O:8][C:9]3[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=3[O:16][CH3:17])=[C:6]([Cl:18])[N:5]=[CH:4][N:3]=2)(=[O:27])=[O:28])=[CH:24][CH:25]=1참가 물질
3
실험 절차
The 4-chloro-N-[6-chloro-5-(5-fluoro-2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide (m.p. 169°-171° C.) was prepared from 4,6-dichloro-5-(5-fluoro-2-methoxy-phenoxy)-pyrimidine and 4-chlorobenzenesulfonamide K.
출처 및 근거
- ORD 기록
- ord-2bdcde6fa2fb44c5b8c6394007bcd438
- 출처 데이터셋
- uspto-grants-1994_03