Acrylamide → 3-[{2-(1,3-Benzodioxol-5-yl)ethyl}thio]propionamide
반응식
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][CH2:11][SH:12])=[CH:9][C:4]=2[O:3][CH2:2]1.[C:13]([NH2:17])(=[O:16])[CH:14]=[CH2:15]>C(O)C>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][CH2:11][S:12][CH2:15][CH2:14][C:13]([NH2:17])=[O:16])=[CH:9][C:4]=2[O:3][CH2:2]1참가 물질
4
실험 절차
5 g of 2-(1,3-benzodioxol-5-yl)ethanethiol and 4 g of acrylamide were dissolved in 100 ml of ethanol and the solution was heated under reflux to conduct the reaction for 20 h. The reaction mixture was cooled with ice. 100 ml of ethanol was added thereto and crystals thus formed were recovered by filtration to obtain 4.2 g of the intended compound in the form of colorless needles.
후처리
- temperaturethe solution was heated
- temperatureunder reflux
- customthe reaction for 20 h
- temperatureThe reaction mixture was cooled with ice
- customcrystals thus formed
- filtrationwere recovered by filtration
출처 및 근거
- ORD 기록
- ord-484311cae6004b7e98f916784b017118
- 출처 데이터셋
- uspto-grants-1994_03
- 특허 번호
- US05292901
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