4-(((2-Chlorophenyl)methyl)amino)-3-nitrobenzoic acid → HCID 19094213, 화합물
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][NH:9][C:10]1[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][C:11]=1[N+:19]([O-])=O>O1CCCC1.C(=O)(O)[O-].[Na+].S([O-])([O-])=O.[Na+].[Na+]>[NH2:19][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:10]=1[NH:9][CH2:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1])[C:14]([OH:16])=[O:15]참가 물질
5
실험 절차
The procedure of Example 2(ii) was followed. From 3.06 (10 mmol) of 4-[(2-chlorophenyl)methyl]amino-3-nitrobenzoic acid in 30 mL of tetrahydrofuran, 25 mL of 5% sodium bicarbonate solution and excess sodium sulfite was obtained 1.93 g (70%) of 3-amino-4-[(2-chlorophenyl)-methyl]aminobenzoic acid; mp 180°-181° C. (from ethyl acetate/hexane).
출처 및 근거
- ORD 기록
- ord-a47bbd60f050499f807c2a81526b8901
- 출처 데이터셋
- uspto-grants-1994_03
- 특허 번호
- US05294631
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