Chlorosuccinimide → 5-Chloro-6 (4-hydroxypiperidino)-3,4-dihydrocarbostyril
반응식
C([O:4][CH:5]1[CH2:10][CH2:9][N:8]([C:11]2[CH:12]=[C:13]3[C:18](=[CH:19][CH:20]=2)[NH:17][C:16](=[O:21])[CH2:15][CH2:14]3)[CH2:7][CH2:6]1)(=O)C.[Cl:22]N1C(=O)CCC1=O>>[Cl:22][C:20]1[CH:19]=[C:18]2[C:13]([CH2:14][CH2:15][C:16](=[O:21])[NH:17]2)=[CH:12][C:11]=1[N:8]1[CH2:9][CH2:10][CH:5]([OH:4])[CH2:6][CH2:7]1.[Cl:22][C:12]1[C:11]([N:8]2[CH2:9][CH2:10][CH:5]([OH:4])[CH2:6][CH2:7]2)=[CH:20][CH:19]=[C:18]2[C:13]=1[CH2:14][CH2:15][C:16](=[O:21])[NH:17]2참가 물질
4
실험 절차
7-Chloro-6-(4-hydroxypiperidino)-3,4-dihydrocarbostyril and 5-Chloro-6 (4-hydroxypiperidino)- 3,4-dihydrocarbostyril were prepared from 6-(4-acetoxypiperidino)-3,4-dihydrocarbostyril in the same procedure as that described in Example 2, except using of N-chlorosuccinimide instead of N-bromosuccinimide.