Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 1-{[(1H-1,2,3-benzotriazol-1-ylmethyl)sulfanyl]methyl}-1H-1,2,3-benzotriazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 1-(Chloromethyl)-1H-benzotriazole | HCID 3328222 | — |
| 반응물 | Sodium sulfide monohydrate | HCID 19906495 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-{[(1H-1,2,3-benzotriazol-1-ylmethyl)sulfanyl]methyl}-1H-1,2,3-benzotriazole | HCID 3766092 | 88% |
반응 단계
1-(Chloromethyl)benzotriazole (20.4 g), prepared above, and sodium sulfide monohydrate (14.4 g) in anhydrous ethanol (75 ml) were stirred overnight (20 hours) at room temperature. Water (240 ml) was added to the reaction mixture. The precipitate was filtered, washed with water to remove inorganic salts and dried. Crystallization from ethanol gave 15.6 g (88%) of desired product (Compound 1); m.p. 179°-181° C. (lit. 182°-184° C.). Thin Layer Chromotography in (CHCl3 /Ethyl acetate) showed only one spot.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05298390 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-21d61f07ab5e409ea3eec212aa4b057a |
| 출처 메모 | uspto-grants-1994_03 |