Toluene → HCID 86747692, 화합물

HRID 487886

반응식

HRID 487886 반응식
[N:1]1[C:10]2[C:5](=[CH:6]C=C[CH:9]=2)[N:4]=CC=1.C[O:12][P:13]([O:16][CH3:17])[O:14][CH3:15].[C:18]1(C)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH3:15][O:14][P:13]([CH2:6][C:5]1[C:10]([CH2:9][P:13](=[O:12])([O:16][CH3:17])[O:14][CH3:15])=[N:1][C:18]2[C:19]([N:4]=1)=[CH:20][CH:21]=[CH:22][CH:23]=2)(=[O:12])[O:16][CH3:17]

참가 물질

4

반응물 3

HCID 1140TolueneHCID 7045QuinoxalineHCID 8472Trimethyl phosphite

생성물 1

HCID 86747692HCID 86747692, 화합물

실험 절차

This known compound is prepared by making a solution of quinoxaline (3.16 g, 10 mmol) in hot toluene (20 ml) and treating with trimethylphosphite (2.73 g, 22 mmol). The mixture is heated at reflux temperature for 24 hours. The cooled solution deposits [2,3-quinoxalindiyl]bis(methylene) bisphosphonic acid tetramethyl ester (2.70 g, m.p. 113°-114° C.) after recrystallization from toluene. V.A. Arbuzov et al. Izvest Acad. Nauk SSSR, 1961, 1016; 1954, E 868; (Chem Abstracts (CA) 55:27352b; CA 49:13222e) report a m.p. 115°-116° C.

후처리

  1. customThis known compound is prepared
  2. temperatureThe mixture is heated
  3. temperatureat reflux temperature for 24 hours
  4. customThe cooled solution deposits [2,3-quinoxalindiyl]bis(methylene) bisphosphonic acid tetramethyl ester (2.70 g, m.p. 113°-114° C.) after recrystallization from toluene

출처 및 근거

ORD 기록
ord-184082a4ebe34e3695e5479f8cc3f369
출처 데이터셋
uspto-grants-1994_03
특허 번호
US05298498

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