Procysteine → (4R)-N-[1-(Nitrooxymethyl)ethyl]-2-oxothiazolidine-4-carboxamide

HRID 487960

반응식

HRID 487960 반응식
[O:1]=[C:2]1[NH:6][C@H:5]([C:7]([OH:9])=O)[CH2:4][S:3]1.[N+]([O-])(O)=O.[N+:14]([O:17][CH2:18][CH:19]([NH2:21])[CH3:20])([O-:16])=[O:15]>>[N+:14]([O:17][CH2:18][CH:19]([NH:21][C:7]([C@@H:5]1[CH2:4][S:3][C:2](=[O:1])[NH:6]1)=[O:9])[CH3:20])([O-:16])=[O:15]

참가 물질

3

반응물 2

HCID 72390ProcysteineHCID 867477001-(Nitrooxymethyl)ethylamine nitrate

생성물 1

HCID 53804780(4R)-N-[1-(Nitrooxymethyl)ethyl]-2-oxothiazolidine-4-carboxamide

실험 절차

A procedure similar to that described in Example 1 was repeated, but using 1.5 g of (4R)-2-oxothiazolidine-4-carboxylic acid and 2.3 g of 1-(nitrooxymethyl)ethylamine nitrate, to obtain 0.35 g of the title compound as colorless crystals, melting at 112°-114° C. (after recrystallization from ethanol).

후처리

  1. customto obtain
  2. custom0.35 g of the title compound as colorless crystals, melting at 112°-114° C. (after recrystallization from ethanol)

출처 및 근거

ORD 기록
ord-e67d54e767a34183b3568da571737d4b
출처 데이터셋
uspto-grants-1994_03
특허 번호
US05298516

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