Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromobenzyl bromide → 1-Bromo-2-(methoxymethyl)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromobenzyl bromide | HCID 76965 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 1-Bromo-2-(methoxymethyl)benzene | HCID 12927162 | — |
반응 단계
685 g (2.74 mol) of o-bromobenzyl bromide was refluxed with 2.74 mol of a 30% strength sodium methylate solution in methanol for 15 hours. After the mixture had cooled to room temperature it was evaporated down, taken up in ethyl acetate, and washed with water. After the organic phase had been dried over sodium sulfate, it was again evaporated down. There was obtained 478.2 g (87%) of the title substance as a colorless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05298527 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-c3460ea5355a4863a64497f82519f589 |
| 출처 메모 | uspto-grants-1994_03 |