4-Bromo-2-ethylaniline → methyl (2Z)-2-(acetylamino)-3-(4-amino-3-isopropylphenyl)acrylate

HRID 488651노트

반응식

HRID 488651 반응식
[CH2:1]([O:8][C:9](=[O:16])[C:10]([NH:12][C:13](=[O:15])[CH3:14])=[CH2:11])C1C=CC=CC=1.Br[C:18]1[CH:24]=[CH:23][C:21]([NH2:22])=[C:20]([CH:25]([CH3:27])[CH3:26])[CH:19]=1.BrC1C=CC(N)=C(CC)C=1>>[C:13]([NH:12]/[C:10](=[CH:11]\[C:18]1[CH:24]=[CH:23][C:21]([NH2:22])=[C:20]([CH:25]([CH3:27])[CH3:26])[CH:19]=1)/[C:9]([O:8][CH3:1])=[O:16])(=[O:15])[CH3:14]

참가 물질

4

반응물 3

HCID 28012834-Bromo-2-ethylanilineHCID 14382052Benzyl 2-(acetylamino)acrylateHCID 222719374-Bromo-2-(propan-2-yl)aniline

생성물 1

HCID 86585325methyl (2Z)-2-(acetylamino)-3-(4-amino-3-isopropylphenyl)acrylate

실험 절차

The titled compound was prepared according to the method described in Example 1B substituting 2-acetylamino-acrylic acid methyl ester for 2-acetylamino-acrylic acid benzyl ester and 4-bromo-2-isopropylaniline for 4-bromo-2-ethylaniline.

출처 및 근거

ORD 기록
ord-f3e6765daba3425f8d23bde943f32c61
출처 데이터셋
uspto-grants-2005_12
특허 번호
US06972340B2

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