Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 2-{4-[(tert-butoxycarbonyl)amino]butoxy}-6-hydroxybenzoate → Trifluoroacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 2-{4-[(tert-butoxycarbonyl)amino]butoxy}-6-hydroxybenzoate | HCID 10980693 | — |
| 반응물 | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| 생성물 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | Methyl 2-(4-aminobutoxy)-6-hydroxybenzoate | HCID 11832643 | — |
반응 단계
Methyl 2-{4-[(tert-butoxycarbonyl)amino]butoxy}-6-hydroxybenzoate (410 mg, 1.2 mmol) was treated with trifluoroacetic acid/dichloromethane (6 mL, 1:1/v:v) at ambient temperature for 3 hours, concentrated under reduced pressure and evaporated with acetonitrile twice to provide the titled amine as its trifluoroacetic acid salt (450 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06972340B2 |
| 출처 데이터셋 | uspto-grants-2005_12 |
| ORD ID | ord-568236dc42d244379cbec0ebfbe7e366 |
| 출처 메모 | uspto-grants-2005_12 |