Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfate → 3-Bromo-4,5-dimethoxybenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfate | HCID 6497 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 5-Bromovanillin | HCID 18099 | — |
| 용매 | Acetone | HCID 180 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 3-Bromo-4,5-dimethoxybenzaldehyde | HCID 81379 | 89% |
반응 단계
To a solution of 5-bromovanillin (2.00 g, 8.65 mmol) in acetone (50 mL) was added potassium carbonate (1.4 g, 10.38 mmol) and dimethylsulfate (1 mL, 10.38 mmol). The solution was stirred at room temperature for 16 hours. The reaction mixture was diluted with ethyl acetate and the organic layer was washed successively with water and brine, dried over anhydrous magnesium sulfate, filtered and evaporated to afford 1.88 g of 3-bromo-4,5-dimethoxybenzaldehyde (89%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06974826B2 |
| 출처 데이터셋 | uspto-grants-2005_12 |
| ORD ID | ord-c76798833fc6472b8a037b56a9eede7b |
| 출처 메모 | uspto-grants-2005_12 |