Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Dimethoxyethane → 3-(3,5-Di-t-butyl-4-hydroxyphenyl)-3-methoxybenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 4-Bromo-2,6-di-tert-butylphenol | HCID 70829 | — |
| 반응물 | 5-Formyl-2-methoxyphenylboronic acid | HCID 2734367 | — |
| 촉매 | HCID 178418397 | HCID 178418397 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-(3,5-Di-t-butyl-4-hydroxyphenyl)-3-methoxybenzaldehyde | HCID 22268285 | 61% |
반응 단계
The intermediate 3-(3,5-di-t-butyl-4-hydroxyphenyl)-3-methoxybenzaldehyde was prepared in a manner similar to the procedure described in Example 1 b using 4-bromo-2,6-di-t-butylphenol (0.50 g, 1.75 mmol), 2-methoxy-5-formylphenyl boronic acid (0.315 g, 1.75 mmol), tetrakis(triphenylphosphine)palladium(0) (0.20 g, 0.175 mmol), K2CO3 (0.95 g, 7.0 mmol), dimethoxyethane (15 mL) and H2O (1 mL); 367 mg, 61% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06974826B2 |
| 출처 데이터셋 | uspto-grants-2005_12 |
| ORD ID | ord-f1cd4724d52f460e9bf5e7053a1f0c30 |
| 출처 메모 | uspto-grants-2005_12 |