2,5-bis(4-methylbenzoyl)terephthalic Acid → 2,5-Bis(4-methylbenzyl)terephthalic acid

HRID 488948노트

반응식

HRID 488948 반응식
[CH3:1][C:2]1[CH:30]=[CH:29][C:5]([C:6]([C:8]2[CH:16]=[C:15]([C:17]([OH:19])=[O:18])[C:14]([C:20](=O)[C:21]3[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=3)=[CH:13][C:9]=2[C:10]([OH:12])=[O:11])=O)=[CH:4][CH:3]=1.[H][H]>[Pd].C(O)(=O)C>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][C:8]2[CH:16]=[C:15]([C:17]([OH:19])=[O:18])[C:14]([CH2:20][C:21]3[CH:22]=[CH:23][C:24]([CH3:27])=[CH:25][CH:26]=3)=[CH:13][C:9]=2[C:10]([OH:12])=[O:11])=[CH:29][CH:30]=1

참가 물질

5

반응물 2

HCID 112581482,5-bis(4-methylbenzoyl)terephthalic AcidHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 117491572,5-Bis(4-methylbenzyl)terephthalic acid

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 176Acetic Acid용매

실험 절차

A mixture of 30.0 grams of 2,5-bis(4-methylbenzoyl)terephthalic acid, 500 mL of acetic acid, and 3 grams of 5% palladium on activated carbon (as a catalyst) was heated to 64° C. for 17 hours in an atmosphere of hydrogen at 270 kPa. The mixture was filtered to remove the catalyst and the product. The catalyst and the product were slurried in 500 mL of tetrahhydrofuran and filtered through Celite™ diatomaceous earth filter agent. The resulting filtrate was concentrated in vacuo. The resulting wet solid was slurried in ethyl acetate and collected by filtration and dried to give 2,5-bis(4-methylbenzyl)terephthalic acid.

후처리

  1. filtrationThe mixture was filtered
  2. customto remove the catalyst
  3. filtrationfiltered through Celite™ diatomaceous earth
  4. filtrationfilter agent
  5. concentrationThe resulting filtrate was concentrated in vacuo
  6. filtrationcollected by filtration
  7. customdried

출처 및 근거

ORD 기록
ord-6d8fde46ea5f4333aa8ec5532b4ba027
출처 데이터셋
uspto-grants-2005_12
특허 번호
US06974877B2

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