Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Phosphate, Tribasic → Butanoic acid, 4-chloro-3-hydroxy-, ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Phosphate, Tribasic | HCID 62657 | — |
| 반응물 | Ethyl 4-chloroacetoacetate | HCID 69484 | — |
| 반응물 | (R)-2-Octanol | HCID 80080 | — |
| 반응물 | Nadh | HCID 439153 | — |
| 생성물 | Butanoic acid, 4-chloro-3-hydroxy-, ethyl ester | HCID 4377704 | — |
반응 단계
100 mM potassium phosphate buffer (pH 6.5), 139.8 mg NADH, 0.06 U (R)-2-octanol dehydrogenase from Candida utilis, and 0.5% 4-chloroacetoacetic acid ethyl ester were reacted overnight at 30° C. The optical purity of the 4-chloro-3-hydroxybutyric acid ethyl ester produced was determined in the same way as Example 32. As a result, 4-chloro-3-hydroxybutyric acid ethyl ester produced by this invention was more than 97% ee of S form.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706507B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-2b07d62153c34136b1cec522d67e3f89 |
| 출처 메모 | uspto-grants-2004_03 |