Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Glycerol → Monostearin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Glycerol | HCID 753 | — |
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Stearoyl chloride | HCID 8212 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Monostearin | HCID 24699 | — |
반응 단계
To a mixture of glycerol (30 g, 326 mmol) and pyridine (25 ml) dissolved in DMF (300 ml) was added dropwise stearoyl chloride (10 g, 33 mmol) dissolved in DMF 100 ml9. The mixture was cooled on an ice bath until addition was complete, whereupon the reaction was maintained under an N2 atmosphere overnight. After 15 hours CH2CL2 (300 ml) and saturated NaHCO3 (aq) was added. The phases were separated and the organic phase washed with water (50 ml) and dried with Na2SO4.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06974802B2 |
| 출처 데이터셋 | uspto-grants-2005_12 |
| ORD ID | ord-e0db80c15c0749028813e3ba995226be |
| 출처 메모 | uspto-grants-2005_12 |