Methyl cyclopropanecarboxylate → 4-(2,1,3-benzoxadiazol-4-yl)-6-cyclopropyl-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

HRID 489413

반응식

HRID 489413 반응식
[CH:1]1([C:4](OC)=O)C[CH2:2]1.[N:8]1[O:9][N:10]=[C:11]2[C:16]([CH:17]=O)=[CH:15][CH:14]=[CH:13][C:12]=12.[NH2:19][C:20]1[CH:24]=[CH:23][NH:22][N:21]=1>>[N:8]1[O:9][N:10]=[C:11]2[C:16]([CH:17]3[C:11]([C:12]#[N:8])=[C:16]([CH:4]4[CH2:1][CH2:2]4)[NH:19][C:20]4=[N:21][NH:22][CH:23]=[C:24]34)=[CH:15][CH:14]=[CH:13][C:12]=12

참가 물질

4

반응물 3

HCID 76122Methyl cyclopropanecarboxylateHCID 102908732,1,3-Benzoxadiazole-4-carbaldehydeHCID 178418806HCID 178418806, 화합물

생성물 1

HCID 1785093654-(2,1,3-benzoxadiazol-4-yl)-6-cyclopropyl-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

실험 절차

The title compound was prepared from methyl cyclopropanecarboxylate, 2,1,3-benzoxadiazole-4-aldehyde and 3-aminopyrazole in the same manner as in Example 94.

출처 및 근거

ORD 기록
ord-35c3ff20399f4900bdf0aee4ee800d6e
출처 데이터셋
uspto-grants-2005_12
특허 번호
US06977262B2

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