2-Iodo-1-methyl-1H-imidazole → 2-(2-Fluoro-phenylethynyl)-1-methyl-1H-imidazole

반응식

I[C:2]1[N:3]([CH3:7])[CH:4]=[CH:5][N:6]=1.[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[F:16])#[CH:9]>>[F:16][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[C:8]#[C:9][C:2]1[N:3]([CH3:7])[CH:4]=[CH:5][N:6]=1

참가 물질

반응물 2

HCID 3358352-Iodo-1-methyl-1H-imidazole

HCID 6433581-Ethynyl-2-fluorobenzene

생성물 1

HCID 98130662-(2-Fluoro-phenylethynyl)-1-methyl-1H-imidazole

실험 절차

The title compound, MS: m/e=201.2 (M+H+) was prepared in accordance with the general method of example 1b from 2-iodo-1-methyl-1H-imidazole and 1-ethynyl-2-fluorobenzene.

출처 및 근거

ORD 기록: ord-5205c5ac3e18434db101aa6b02596a34
출처 데이터셋: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06706707B2

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