Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 5-carboxymethoxy-1H-indole-2-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 5-tert-butoxycarbonylmethoxy-1H-indole-2-carboxylic acid ethyl ester | HCID 69587439 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 5-carboxymethoxy-1H-indole-2-carboxylic acid ethyl ester | HCID 69586665 | 101.3% |
반응 단계
A mixture of 5-tert-butoxycarbonylmethoxy-1H-indole-2-carboxylic acid ethyl ester (2 g, 6 mmol) and trifluoroacetic acid (8 mL) in dichloromethane (8 mL) was stirred at room temperature for 2 hours. The reaction was concentrated to give 1.6 g (97%) of 5-carboxymethoxy-1H-indole-2-carboxylic acid ethyl ester as a light brown solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706709B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-97e0e3d6a9364f4f8edc82a1239805fa |
| 출처 메모 | uspto-grants-2004_03 |