Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
[5-(3-diethylamino-propyl)-1H-indol-2-yl]-methanol → 5-(3-diethylamino-propyl)-1H-indole-2-carbaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | [5-(3-diethylamino-propyl)-1H-indol-2-yl]-methanol | HCID 22042151 | — |
| 촉매 | Manganese oxide | HCID 160959 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 5-(3-diethylamino-propyl)-1H-indole-2-carbaldehyde | HCID 22042114 | 86.1% |
반응 단계
Manganese oxide (3.75 g, 43.1 mmol) was added portionwise to [5-(3-diethylamino-propyl)-1H-indol-2-yl]-methanol (660 mg, 2.53 mmol) dissolved in dichloromethane (68 mL) under nitrogen at room temperature. The precipitate was filtered through celite, washing with hot dichloromethane. The filtrate was concentrated to give 563 mg (83%) of 5-(3-diethylamino-propyl)-1H-indole-2-carbaldehyde as a waxy brown solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706709B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-d60fafba983a46b6afe1da41a9ce5d74 |
| 출처 메모 | uspto-grants-2004_03 |