참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Citric Acid | HCID 311 | — |
| 반응물 | 4-Methoxy-3-(trifluoromethyl)benzoic acid | HCID 2775295 | — |
| 생성물 | 4-Hydroxy-3-(trifluoromethyl)benzoic acid | HCID 2775112 | — |
반응 단계
10.0 g (45.4 mmol) 4-methoxy-3-trifluoromethyl-benzoic acid and 75 g pyridinium-hydrochloride were mixed well and then heated to 180° C. under a nitrogen atmosphere for 5 h. The reaction mixture was poured onto 1 L 10% citric acid solution and extracted with 50 mL EtOAc. The organic phase was washed with 1 L water and dried over Na2SO4. After the desiccant and solvent had been eliminated the product was further reacted without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07528129B2 |
|---|
| 출처 데이터셋 | uspto-grants-2009_05 |
|---|
| ORD ID | ord-3592c36111624b0c9a30edf57426b151 |
|---|
| 출처 메모 | uspto-grants-2009_05 |
|---|
