Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → Diethyl 4-Bromo-2-methylbenzylphosphonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | Phosphonic acid, P-((2-methylphenyl)methyl)-, diethyl ester | HCID 112945 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Trimethyl Phosphate | HCID 10541 | — |
| 생성물 | Diethyl 4-Bromo-2-methylbenzylphosphonate | HCID 19797190 | — |
반응 단계
10 g (42 mmol) of diethyl 2-methylbenzylphosphonate were dissolved in 60 ml of trimethyl phosphate and the solution was introduced into a flask protected from light and moisture. 16 g (0.05 mol) of Br2 were added dropwise, while stirring. The mixture was stirred at 90° C. for 15 hours and, after cooling, was diluted with 100 ml of water and extracted three times with 100 ml of n-hexane each time. The organic phase wa dried, concentrated and distilled.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05242908 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-d600937ba404454f851cb18c5c96b0b1 |
| 출처 메모 | uspto-grants-1993_09 |