1-methyl-1H-indazol-5-amine → HCID 10428594, 화합물

HRID 491573

반응식

HRID 491573 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=O)=[C:10]([CH3:17])[N:9]=2)=[CH:4][CH:3]=1.[NH2:18][C:19]1[CH:20]=[C:21]2[C:25](=[CH:26][CH:27]=1)[N:24]([CH3:28])[N:23]=[CH:22]2>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([NH:18][C:19]3[CH:20]=[C:21]4[C:25](=[CH:26][CH:27]=3)[N:24]([CH3:28])[N:23]=[CH:22]4)=[O:14])=[C:10]([CH3:17])[N:9]=2)=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 27680321-methyl-1H-indazol-5-amineHCID 242777906-(4-Fluorophenyl)-2-methylpyridine-3-carboxylic acid

생성물 1

HCID 10428594HCID 10428594, 화합물

실험 절차

Using the procedure outlined in Example 15, the title compound was prepared from 6-(4-fluorophenyl)nicotinic acid (D3) (100 mg, 0.43 mmol) and 5-amino-1-methylindazole (58 mg, 0.39 mmol) as a white solid (21 mg). MS (ES): MH+ 361, (M−H)− 359.

출처 및 근거

ORD 기록
ord-6a07dc36a3e74f7db9aea3b362208bca
출처 데이터셋
uspto-grants-2009_05
특허 번호
US07531558B2

연결된 노트

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