1,8,8-Trimethyl-3-oxabicyclo[3.2.1]octane-2,4-dione → HCID 10408650, 화합물

HRID 4917

반응식

HRID 4917 반응식
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][N:9]([C:12]2[N:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[CH2:8][CH2:7]1.[CH3:18][C:19]1([CH3:30])[C:23]2([CH3:29])[C:24]([O:26][C:27](=O)[CH:20]1[CH2:21][CH2:22]2)=[O:25]>>[N:17]1[CH:16]=[CH:15][CH:14]=[N:13][C:12]=1[N:9]1[CH2:8][CH2:7][N:6]([CH2:5][CH2:4][CH2:3][CH2:2][N:1]2[C:27](=[O:26])[CH:20]3[C:19]([CH3:18])([CH3:30])[C:23]([CH3:29])([CH2:22][CH2:21]3)[C:24]2=[O:25])[CH2:11][CH2:10]1

참가 물질

3

반응물 2

HCID 948341,8,8-Trimethyl-3-oxabicyclo[3.2.1]octane-2,4-dioneHCID 128407054-(2-Pyrimidinyl)-1-piperazinebutanamine

생성물 1

HCID 10408650HCID 10408650, 화합물수율 17%

실험 절차

The title compound was prepared from 2.47 g (10.4 mmol) of 1-(4-aminobutyl)-4-(2-pyrimidinyl)piperazine and 1.89 g (10.3 mmol) of dl-camphoric anhydride, substantially according to the procedure of Example 1. This afforded 0.7 g of product, mp 94°-97° C. (17% yield).

출처 및 근거

ORD 기록
ord-88cb2fb8067f482b8c767b3656f1557f
출처 데이터셋
uspto-grants-1993_09
특허 번호
US05242911

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