7-Bromo-5-methoxy-2-(4-methoxyphenyl)-1,3-benzoxazole → HCID 135445365, 화합물

반응식

Br[C:2]1[C:10]2[O:9][C:8]([C:11]3[CH:16]=[CH:15][C:14]([O:17]C)=[CH:13][CH:12]=3)=[N:7][C:6]=2[CH:5]=[C:4]([O:19]C)[CH:3]=1.Br[Zn][CH:23]1[CH2:27][CH2:26][CH2:25][CH2:24]1>>[CH:23]1([C:2]2[C:10]3[O:9][C:8]([C:11]4[CH:12]=[CH:13][C:14]([OH:17])=[CH:15][CH:16]=4)=[N:7][C:6]=3[CH:5]=[C:4]([OH:19])[CH:3]=2)[CH2:27][CH2:26][CH2:25][CH2:24]1

참가 물질

반응물 2

HCID 121489697-Bromo-5-methoxy-2-(4-methoxyphenyl)-1,3-benzoxazole

HCID 178419769HCID 178419769, 화합물

생성물 1

HCID 135445365HCID 135445365, 화합물

실험 절차

The title compound was prepared in substantially the same manner as described in Example 35, from 7-bromo-5-methoxy-2-(4-methoxyphenyl)-1,3-benzoxazole, and bromo(cyclopentyl)zinc. The desired product was obtained as a white solid, m.p. 220-222° C.; MS m/e 296 (M+H)+.

후처리

customThe title compound was prepared in substantially the same manner

출처 및 근거

ORD 기록: ord-13274f1f68754ff190009cd724f8ed82
출처 데이터셋: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07531564B2

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