Trifluoroacetyl fluoride → 3,3-Difluoro-3-pentafluoroethoxy-2-trifluoromethylpropene

HRID 492271

반응식

HRID 492271 반응식
[F:1][C:2]([F:7])([F:6])[C:3]([F:5])=[O:4].[F-:8].[K+].[CH2:10]=[C:11]([C:16](OS(F)(=O)=O)([F:18])[F:17])[C:12]([F:15])([F:14])[F:13]>COCCOCCOC>[F:17][C:16]([F:18])([O:4][C:3]([F:8])([F:5])[C:2]([F:7])([F:6])[F:1])[C:11]([C:12]([F:15])([F:14])[F:13])=[CH2:10]

참가 물질

5

반응물 3

HCID 67716Trifluoroacetyl fluorideHCID 522689Potassium FluorideHCID 87741755CH2=C(CF3)CF2Oso2F

생성물 1

HCID 858876563,3-Difluoro-3-pentafluoroethoxy-2-trifluoromethylpropene수율 31%

시약·촉매·용매 1

HCID 8150Diglyme용매

반응 조건

온도
20 °C

실험 절차

Trifluoroacetyl fluoride (6 g, 0.051 mole) is bubbled into a mixture of KF (2.4 g, 0.041 mole) and dry diglyme (15 ml). The reaction mixture is stirred at 20° C. for 30 minutes and then CH2═C(CF3)CF2OSO2F (10 g, 0.041 mile) is added gradually. The resulting mixture is stirred at 20° C. for 1 hour. Hexafluoroisobutylene is distilled from the reaction mixture and the residue is poured into water. The organic layer. is separated, washed in turn with aqueous sodium bicarbonate solution and water, and then dried over MgSO4. Distillation gives 3,3-Difluoro-3-pentafluoroethoxy-2-trifluoromethylpropene (CH2═C(CF3)CF2OCF2CF3) (3.5 g, 31% yield, b.pt. 67° C.).

후처리

  1. stirringThe resulting mixture is stirred at 20° C. for 1 hour
  2. distillationHexafluoroisobutylene is distilled from the reaction mixture
  3. additionthe residue is poured into water
  4. customis separated
  5. washwashed in turn with aqueous sodium bicarbonate solution and water
  6. dry with materialdried over MgSO4
  7. distillationDistillation

출처 및 근거

ORD 기록
ord-aaafe8030fd246c1927a22706221032d
출처 데이터셋
uspto-grants-2009_05
특허 번호
US07531689B2

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