Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → Esomeprazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Omeprazole | HCID 4594 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Esomeprazole | HCID 9568614 | — |
반응 단계
The procedure set forth in Example 2 is repeated except that ethanol is employed as a solvent in place of DMF and the resulting structure is shown by various X-ray crystal diffraction and/or Raman spectroscopy to contain between about 82 and 85 percent (w/w) of 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole and between about 15 and 18 percent (w/w) of 5-methoxy 2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706737B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-d0cef4e0486c4bbdbeb13ef531fd5ee2 |
| 출처 메모 | uspto-grants-2004_03 |