Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → 2-{[2-(Allyloxy)-4-(benzyloxy)phenoxy]methyl}oxirane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | Glycidyl tosylate, (R)- | HCID 154187 | — |
| 반응물 | 2-Allyloxy-4-(benzyloxy)phenol | HCID 18546012 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Hexane | HCID 8058 | — |
| 생성물 | 2-{[2-(Allyloxy)-4-(benzyloxy)phenoxy]methyl}oxirane | HCID 18546022 | — |
반응 단계
Sodium hydride (4.3 g, 0.11 mole of 60% mineral oil dispersion) was washed with hexane and suspended in 100 mL of N,N-dimethylformamide. To this suspension was added a solution of 25.4 g (0.10 mole) of 2-allyloxy-4-(benzyloxy)phenol in 100 mL of DMF. The mixture was stirred at room temperature for 30 minutes and then 22.8 g (0.10 mole) of (2R)-(−)-glycidyl tosylate was added.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706736B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-6233de2de6f143688edd4dcfaa46e9b9 |
| 출처 메모 | uspto-grants-2004_03 |