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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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1-Methyl-3-(2',2',2'-trifluoroethyl)imidazolium triflate → 1-methyl-3-(2',2',2'-trifluoroethyl)imidazolium N-(trifluoromethanesulfonyl)-trifluoroacetamide

HRID 493021
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HRID 493021 반응식
[O-]S(C(F)(F)F)(=O)=O.[CH3:9][N+:10]1[CH:14]=[CH:13][N:12]([CH2:15][C:16]([F:19])([F:18])[F:17])[CH:11]=1.[F:20][C:21]([F:33])([F:32])[S:22]([NH:25][C:26](=[O:31])[C:27]([F:30])([F:29])[F:28])(=[O:24])=[O:23].[Na]>O>[F:32][C:21]([F:20])([F:33])[S:22]([NH:25][C:26](=[O:31])[C:27]([F:28])([F:29])[F:30])(=[O:24])=[O:23].[CH3:9][N+:10]1[CH:14]=[CH:13][N:12]([CH2:15][C:16]([F:18])([F:17])[F:19])[CH:11]=1
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4

반응물 2

HCID 866047831-Methyl-3-(2',2',2'-trifluoroethyl)imidazolium triflateHCID 86604785sodium N-(trifluoromethanesulfonyl)trifluoroacetamide

생성물 1

HCID 866047841-methyl-3-(2',2',2'-trifluoroethyl)imidazolium N-(trifluoromethanesulfonyl)-trifluoroacetamide

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

1-Methyl-3-(2′,2′,2′-trifluoroethyl)imidazolium triflate (10 mmol) and water (10 ml) were placed in a reaction vessel, and a solution of sodium N-(trifluoromethanesulfonyl)trifluoroacetamide (2.94 g, 11 mmol) and water (3 ml) were added thereto while stirring. The mixture was then stirred for 15 minutes. The lower oil layer was separated, and this layer was repeatedly washed with water. The obtained oil product was dehydrated using a vacuum pump at 110° C. for 3 hours, and 1-methyl-3-(2′,2′,2′-trifluoroethyl)imidazolium N-(trifluoromethanesulfonyl)-trifluoroacetamide (compound 12) was obtained (yield 2.87 g, 70%). When further purification is required, the oil product may be dissolved in a small amount of ethyl acetate, and a large amount of ether may be added thereto to separate the oil product and the product may be dried. Alternatively, when the product is colored, it may be treated with active carbon. Physical property, elemental analysis and spectral data of the compound 12 are shown in Table 8.

후처리

  1. stirringThe mixture was then stirred for 15 minutes
  2. customThe lower oil layer was separated
  3. washthis layer was repeatedly washed with water
  4. customat 110° C.
  5. customfor 3 hours

출처 및 근거

ORD 기록
ord-1cb7d695b85d44cab348bbf65644974a
출처 데이터셋
uspto-grants-2009_05
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US07534509B2

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