(S)-7-Benzyloxymethoxy-2,6-dimethyl-heptan-2-ol → HCID 20554058, 화합물
반응식
C(OC[O:10][CH2:11][C@@H:12]([CH3:20])[CH2:13][CH2:14][CH2:15][C:16]([CH3:19])([OH:18])[CH3:17])C1C=CC=CC=1>C(OCC)(=O)C.[Pd]>[CH3:20][CH:12]([CH2:13][CH2:14][CH2:15][C:16]([CH3:19])([OH:18])[CH3:17])[CH2:11][OH:10]참가 물질
4
실험 절차
To a solution of an alcohol 7 (1.8 g, 0.01 mol) in ethyl acetate (20 mL) was added Pd/C (10%, 100 mg) at room temperature. The reaction mixture was stirred for 5 days and Pd/C (150 mg) was added 3 times per day. The reaction was then filtered, and the solvent was evaporated under reduced pressure. The crude oil was chromatographed on silica gel using hexane/EtOAc (1:1) as an eluent to give an oily diol 8 (0.95 g, 92%).
후처리
- filtrationThe reaction was then filtered
- customthe solvent was evaporated under reduced pressure
- customThe crude oil was chromatographed on silica gel
출처 및 근거
- ORD 기록
- ord-2fe352c4f38f43b2a9cd322f78886621
- 출처 데이터셋
- uspto-grants-2009_05
- 특허 번호
- US07534777B2
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