Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Iodide → 84422-52-6
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Iodide | HCID 5238 | — |
| 반응물 | 2,4-Dimethoxy-5-methylbenzaldehyde | HCID 251692 | — |
| 반응물 | Aluminum(III) Chloride | HCID 6451240 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 84422-52-6 | HCID 13166819 | — |
반응 단계
The above prepared 2,4-Dimethoxy-5-methyl-benzaldehyde (5.40 g, 30 mmol) was dissolved in 150 mL of acetonitrile and treated successively with sodium iodide (6.74 g, 1.5 eq.) and AlCl3 (4.00 g, 1.0 eq.), and the mixture kept at 80° C. for 1 h. Cooling, pouring onto crashed ice, twofold extraction with AcOEt, washing with water and brine, drying over magnesium sulfate, and evaporation of the solvents, followed by flash chromatography (SiO2, hexane/AcOEt=9/1), delivered 4.23 g of the title compound as light brown crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07534788B2 |
| 출처 데이터셋 | uspto-grants-2009_05 |
| ORD ID | ord-11a5a2acbeae4b778a041cb41b2954dc |
| 출처 메모 | uspto-grants-2009_05 |