Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cesium bicarbonate → (2s)-2-[(Tert-butoxy)carbonylamino]-3-[3,4-bis(phenylmethoxy)phenyl]propionic acid cesium salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cesium bicarbonate | HCID 2734983 | — |
| 반응물 | N-(tert-Butoxycarbonyl)-3,4-dibenzyloxyphenylalanine | HCID 12968276 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | (2s)-2-[(Tert-butoxy)carbonylamino]-3-[3,4-bis(phenylmethoxy)phenyl]propionic acid cesium salt | HCID 87312671 | — |
반응 단계
Cesium hydrogencarbonate (194 mg, 1 mmol) was added to a solution of (2S)-2-[(tert-butoxy)carbonylamino]-3-[3,4-bis(phenylmethoxy)phenyl]propionic acid (297 mg, 1 mmol) in 5 mL water and 5 mL acetonitrile. The resulting mixture was stirred at room temperature for 10 minutes, then frozen and lyophilized to yield (2S)-2-[(tert-butoxy)carbonylamino]-3-[3,4-bis(phenylmethoxy)phenyl]propionic acid cesium salt as a white solid, which was used in the next reaction without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07534813B2 |
| 출처 데이터셋 | uspto-grants-2009_05 |
| ORD ID | ord-4af22bc9bef84e65800bc1d634636766 |
| 출처 메모 | uspto-grants-2009_05 |