Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromo-2-propionylthiophene → (e)-5-(4-Bromo-2-thienyl)-4-heptenoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromo-2-propionylthiophene | HCID 818932 | — |
| 반응물 | (3-Carboxypropyl)(triphenyl)phosphanium bromide | HCID 10717451 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 생성물 | (e)-5-(4-Bromo-2-thienyl)-4-heptenoic acid | HCID 69824575 | — |
반응 단계
In a manner similar to that of Example 6(i), by reaction of 16 g (73 mmol) of 1-(4-bromo-2-thienyl)-1-propanone with 47 g (109 mmol) of (3-carboxypropyl)triphenylphosphonium bromide and 24.6 g (219 mmol) of potassium tert-butoxide, the desired product is obtained in the form of an orange-coloured solid (m=16.7 g; Y=80%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706725B1 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-c0f09115b91b438eb34c750a94d27c15 |
| 출처 메모 | uspto-grants-2004_03 |